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Monobactam :

Monobactams

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Aztreonam. (The square is the beta-lactam. There is a second thiazole ring, but it is not fused to the beta-lactam ring)

Monobactams are beta-lactam antibiotics wherein the beta-lactam ring is alone, and not fused to another ring (in contrast to most other beta-lactams, which have at least two rings). The only commercially available monobactam is aztreonam.

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Antibacterials: cell wall disruption (J01C-J01D)
Internal to membrane/
(inhibit peptidoglycan subunit
synthesis and transport)
NAM synthesis inhibition
Bactoprenol inhibitors
Glycopeptide/
(inhibit PG chain elongation)
Beta-lactams/
(inhibit cross-links
with PBP)
Monobactams
Combinations
Other
Hydrolyze NAM-NAG
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